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December 2023

BDL and BiS at end year festivities 2023

We celebrated the x-mas with a potluck lunch where we organized an image contest for our 2024 calendar. With the tasty food, it was great to vote for the best images captured by the group members. Special thanks to Doke for organizing this event!

December 2023

We got an NWO XS grant awarded!

With this funded grant, we will develop better hydrogel-integrated microfluidic platforms to examine cell-material interactions. Our focus will be the interplay between the stiffness and hydrogel adaptability for the control of cell behavior. 

November 2023

Congrats Oksana for being selected to deliver a talk in 7th Annual hDMT Meeting.

hDMT is a national consortium to excel organ on chip research in the Netherlands. Oksana will present us with her digital microfluidic platform study.

October 2023

Esmée defended her M.Sc. thesis successfully. Congrats!

Esmée modeled the three-dimensional (3D) microenvironment of spinal cord injury using a microfluidic chip. 

September 2023

We got a Horizon Europe CoFund grant awarded!

In a team of researchers from Sabanci University Nanotechnology Research and Application Center (SUNUM), TUBITAK Marmara Research Center (TUBITAK-MAM), Koç University Research Center for Translational Medicine (KUTTAM) and Izmir Biomedicine and Genome Center (IBG), we got a funding of 3,7 million Eur from Horizon Europe CoFund program. The topic is about developing "Nanobiotechnologies for Innovative Therapeutic Approaches for Cancer". The program focuses on cancer research while providing a tailor-made accelerator programme to educate tomorrow’s researchers in a broad set of scientific, transferable, and business skills to develop the mindset of an entrepreneur in parallel to the academic career. 

We are looking forward to collaborating with excellent researchers in the next 5 years!

July 2023

Oksana is an invited member of the organization committee of SAFE/ProRISC conference 2024.

In 2023, the conference took place -  and Oksana presented a poster

 

July 2023

Congrats to our MicroTAS 2023 poster presenters Lanhui, Mert and Oksana.

June 2023

Carina is on ICMS news!

Ana Carina Manjua fell in love with biomedical research during her master's at the New University of Lisbon, when studying electroconductive materials as biobatteries for pacemakers. During her PhD at the Instituto Superior Técnico in the same city, she worked on building a microchip to regenerate blood vessels. After that, she worked 1.5 years in a biomaterials company. Manjua returned to research last March as a EuroTech postdoc at the TU/e Biosensors and Devices Lab.
She will again work on microchips, this time in the context of cardiovascular diseases. The goal is to remodel cardiac tissue on a chip and recreate its micro-environment in order to simulate the disease and find ways to regenerate the tissue. Manjua’s research will include the microchip design, developing a hydrogel for electromagnetic stimulation to regenerate cells, building a stretchable platform – at the Swiss University EPFL – to simulate cardiac rhythm, and arranging a computational interface, before she can actually study the cardiac tissue.

June 2023

We are on the local news for innovative teaching.

Our lab developed an interdepartmental and highly hands-on challenge-based learning course on Lab on a Chip Microdevices. We happily share the interview with Cursor magazine.

June 2023

Burcu delivers an invited talk at GRC Physics and Chemistry of Microfluidics Edition 2023.

This talk covered how we handle the digital microfluidics systems in the scope of regenerative medicine and our attempt to improve the system to create unique cellular microenvironments. We are honored to be a part of this community! Looking forward to joining the next editions.

March 2023

Happy 3 years BDL! We went for an amazing research retreat.

During the research retreat, we talked about the group dynamics,  research attitude, and made some planning. We also made teambuilding activities, which were also definitely lots of fun!

March 2023

We join the annual symposium by Institute for Complex Molecular Systems at TU/e.

BDL is a  Institute for Complex Molecular Systems (ICMS) affiliate & enjoy making science together. This year the annual event is hosted by all TU/e-based exciting speakers on 30-31 March 2023. Burcu co-chairs the first day of the event. Feel free to join us!

March 2023

Paper alert! Our collaboration with Radboud UMC resulted in a Biosensors paper, just published. Congrats to all authors.

In the paper entitled "Co-culture of glomerular endothelial cells and podocytes in a custom-designed glomerulus-on-a-chip model improves the filtration barrier integrity and affects the glomerular cell phenotype", we build a functional microfluidic environment supported with perforated polycarbonate membrane to rebuild glomerulus units in the kidney. Lanhui and Burcu contributed to this work in the design and fabrication phases. 

March 2023

Carina Manjua joins our group as a postdoctoral fellow. Welcome, Carina!

February 2023

2023 winter season group outing at BDL and BiS.

Members of Biosensors and Devices Lab and Biointerface Science went on the ice. Some of us skated hard, others sent their good wishes from the sideline. Either way was fun!

February 2023

BDL's first BEP students graduate successfully!

Our lab's first bachelor end project students Tess, Valerie, and Christian graduated successfully! They collaboratively worked on materials to mimic ECM and how the stiffness of the environment relates to cell behavior from different perspectives including diffusion time, cell morphology, and stiffness changes.  Their studies were guided by Oksana and Esmee. Well done! 

November 2022

End year potluck lunch and calendar contest at BDL and BiS 2022 was so much fun.

Having a multicultural group comes with its perks. This year we joined forces with BiS and everyone baked or cooked their favorite dishes. The end result was amazingly delicious!

We also voted for the best images right out of the lab, submitted by our members. The new year's calendar is in the making with original art! Such a happy ending to 2022. 

November 2022

Emy successfully defends her M.Sc. thesis.

Emy worked on light-responsive dynamic surfaces embedded in microfluidics platform to study immune cell-material interactions during her studies. She found that macrophages respond to height and stiffness changes at various levels.

November 2022

Ruth Verbroekken joins BDL as a joint Ph.D. student! Welcome, Ruth!

Ruth will work on developing light-responsive surface patterns, which will be integrated into a microfluidic platform to explore the cell-material response of macrophages. Ruth is a joint Ph.D. student of the Chemical Engineering and Biomedical Engineering Departments. 

November 2022

Mert Ozden joins our lab as a Ph.D. candidate. He will be working on innovating the digital microfluidic platform for high content screening. Heartily welcome, Mert!

October 2022

Congratulations Lanhui on being selected to deliver an oral presentation at NBTE conference 2022.

October 2022

BDL exhibits at Dutch Design Week 2022 in collaboration with designer Piet Hein Eek.

 This year we collaborate with Dutch designer Piet Hein Eek to demonstrate atherosclerosis-on-chip.  Dutch Design week is held between 22-30 October 2022.

How does “design” change its meaning in functional (or a word that Piet prefers) and scientific perspectives?

Through our journey to bring different designers collaborating, we noticed that the word “design” can bear different meanings. Therefore, we share what we found out: Piet (PHE) and Burcu (Eindhoven University of Technology, Biomedical Engineering Department) joined forces to approach functional design from different perspectives. While Piet is good at designing macro-scale objects that find use in households, Burcu designs micro-scale objects for research purposes.  

For Piet, design is a word to create a functional product that he can foresee its use, while for Burcu design is a word to create a functional platform to explore the unforeseen, mostly for the understanding of medical problems.

Hereby, Piet and Burcu present a micron-scale construct made using the logo of Piet Hein Eek (PHE). This design mimics the branching veins in the body to study atherosclerosis, a health-related disorder resulting in clogged veins, which require the placement of stents. The logo of PHE appeared as an easy-to-fabricate and -operate design, therefore it was interesting to choose it to model the blood flow velocity in veins.

Through simulations, we found that the branching sides having a slower flow rate when compared to the main channels. Through experiments, real cells reacted to the flow by accumulating in low-flow-rate regions and migrating in high-flow rate regions. Our observation is in accordance with medical findings that regions with more cell accumulation were predicted to be more prone to atherosclerosis. Therefore, we can use this model to study the biology of this disease further and propose new treatment strategies!

October 2022

Heartily welcome to Guillem Monso who will develop AI-Brain on chip platform in his Ph.D. work!

October 2022

Esmee Meijerhof successfully defends her M.Sc. thesis.

Esmee worked on the development of a pulse-on-chip microfluidic platform with magnetic hydrogel valve to study mechanobiology during her M.Sc. studies. Today She successfully defended her work. We were really happy to have her around! Good luck with your future work Esmee, but before it is the well-deserved holiday time!

September 2022

We kicked off the Lab on a Chip Microdevices course.

This year, we run a pilot of the Lab on a Chip Microdevices course. Today we finished the first lab session, and it was so much fun to make chips together. Our student team is dealing with a real problem assigned by Emultech, a high-tech campus company. The project is about generating stable water-in-water droplets. This challenge could not be easier without the help of Lanhui and Kalpit. Exciting!  

September 2022

Esmée van der Vliet joins our team as a M.Sc. student. Welcome, Esmée!

She will be working on building a glial scar on chip using hydrogels with different stiffness properties. 

July 2022

Paper out! We publish a review paper on engineering organ-on-a-chip to accelerate translational research.

With our collaborator Prof. Noo Li Jeon at Seoul National University, we prepared an educational review paper on engineering organ-on-a-chip to accelerate translational research.  We provide an overview of what is organ-on-chip, where it can be used, what it is composed of, how it can be fabricated, and how it can be operated. We also revisited the recent applications, where different organs are modeled on the microscale using this technology.

July 2022

We got an EuroTech2Postdoc application granted!

Carina will join our lab in February 2023 to work on high-throughput stimuli-responsive screening microchips for cardiac tissue remodeling in collaboration with our partners at EPFL and TU/e Biomedical Engineering. 

July 2022

Burcu joins the review editorial board of Frontiers in Lab on a Chip Technologies Journal.

July 2022

Minne successfully defends her M.Sc. thesis.

In her M.Sc. work, Minne assessed the dynamic interplay of shear stress and surface topographies on hepatocytes in a microfluidic platform.

May 2022

Website for the Digital Twins in Healthcare Course is online now! Our lab runs the conceiving phase of the course.

May 2022

Burcu joins the Technical Program Committee of MicroTAS. BDL is looking forward to contributing to the pioneering conference in Lab on a chip world!

May 2022

Our lab is awarded with a BOOST! grant for education. We are excited to develop the brand-new Lab on a chip course!

May 2022

NWO Gravitation funding was granted for ICMS consortia, including our lab!

March 2022

Burcu gives a Keynote talk at the Netherlands Society for Biomaterials and Tissue Engineering (NBTE) 30th Annual Meeting.

NBTE is a society that aims to promote the interests of biomaterials science and tissue engineering in the Netherlands and to stimulate cooperation between universities, institutions and industries in these domains. In 2022, NBTE is celebrating the 30st anniversary! 

Burcu's Keynote is about Lab on a Chip Devices for Bioclinical Applications. Follow the link below for more information.

January 2022

Oksana is selected to attend SCOPE 2022 organized by Northwestern University (USA). Congrats Oksana!

January 2022

Burcu is elected as a member of biomedical engineering departmental council at TU/e.

December 2021

Biosensors and Devices Lab is in Christmas lunch group outing in 2021.

November 2021

Joska Aerts defends her M.Sc. thesis successfully. She is the first M.Sc. graduate of Biosensors and Devices Lab!

In her thesis, she embedded surface patterns into custom-designed microfluidic chip to enable long-term hepatocyte cultures.

Joska will continue her journey in professional life at Genmab as a research associate in cell banking and transient production. 

October 2021

Oksana Savchak joins as the first Ph.D. candidate of Biosensors and Devices Lab. Welcome, Oksana!

October 2021

Burcu is invited as a Community Engagement Committee member and poster judge committee member at MicroTAS 2021.

September 2021

Esmee Meijherhof joins Biosensors and Devices Lab as a M.Sc. student. Welcome, Esmee!

May 2021

Lanhui Li joins Biosensors and Devices Lab as a postdoc. Welcome, Lanhui!

May 2021

Minne Dekker joins Biosensors and Devices Lab as a M.Sc. student. Welcome, Minne!

May 2021

Burcu is awarded EAISI EMDAIR grant in collaboration with Mechanical Engineering and Computer Science Departments at TU/e.

February 2021

Emy Curvers joins Biosensors and Devices Lab as a M.Sc. student. Welcome, Emy!

February 2021

Burcu is awarded Immunoengineering grant at TU/e.

January 2021

I Fon Bambang joins as a lab administrator to the BiS group and Biosensors and Devices Lab. Welcome, I Fon!

December 2020

Burcu serves as a co-editor for Micromachines Journal special edition called “Recent advances in electrokinetic mifrofluidic devices” which has a submission deadline in July 2021.

This task is a collaboration between TU/e, University of Oulu, and University of Rome Tor Vergata.

November 2020

Burcu is invited as a topic editor in Micromachines journal.

October 2020

Burcu is invited as a poster judge committee member at MicroTAS 2020.

September 2020

Joska Aerts joins as the first M.Sc. student of the Biosensors and Devices Lab. Welcome, Joska!

May 2020

Burcu is awarded Irene Curie Fellowship grant.

April 2020

The first day of the Biosensors and Devices Lab at TU/e!